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quinta-feira, 21 de agosto de 2008

Fast food shops urged to go healthy as children continue to choose chips

The Scottish Government is being urged to encourage fast food shops to offer healthy options in a bid to help tackle child obesity. In a survey of 146 14 to 16-year-olds the Scottish Consumer Council (SCC) found that more than 50 per cent leave school grounds to go to surrounding shops for lunch. Its report, published today, revealed in rural, large town and new town areas pupils go straight for pizza, chips, chocolate and crisps for their midday meal. The watchdog has asserted a new meals strategy that reaches beyond the school gates is needed. It also found that students in this age group eat outside of school for choice, to get away from noisy canteens and for social reasons. Following the study, the Council is now appealing to locals shops to stock healthy alternatives. SCC chairman Douglas Sinclair said: "These are young adults learning to make important decisions about their diet and they need help to make the right choices. While the key to improving lunchtime choices for Scotland’s teenagers is about supporting them with the information about good food and healthy eating, the Scottish Government and local councils have to play their part as well. "Surely this is an opportunity for local retailers to offer healthier 'on the go' options at affordable prices for the young people who make a positive choice to eat away from school."

quarta-feira, 20 de agosto de 2008

Some fruit juices can harm drug absorption: study

Grapefruit, orange and apple juices can harm the body's ability to absorb certain medications and make the drugs less effective, said a Canadian study released in the United States.

The research showed that these juices can decrease the effectiveness of certain drugs used to treat heart disease, cancer, organ-transplant rejection and infection, "potentially wiping out their beneficial effects," it said.
David Bailey, a professor of clinical pharmacology with the University of Western Ontario and leader of the study, was the first researcher to identify grapefruit juice's potential to increase the absorption of certain drugs two decades ago, possibly turning some doses toxic.
The new findings came as part of his continuing research on the subject, and were presented at the 236th annual meeting of the American Chemical Society on Philadelphia, Pennsylvania.
"Recently, we discovered that grapefruit and these other fruit juices substantially decrease the oral absorption of certain drugs undergoing intestinal uptake transport," said Bailey.
"The concern is loss of benefit of medications essential for the treatment of serious medical conditions."
Healthy volunteers took fexofenadine, an antihistamine used to fight allergies, along with either a glass of grapefruit juice, a glass of water with naringin (which gives the bitter taste to grapefruit juice), or plain water.
Those who drank the grapefruit juice absorbed only half the amount of fexofenadine, compared to those who drank plain water.
Researchers said the water with naringin served to block "a key drug uptake transporter, called OATP1A2, involved in shuttling drugs from the small intestine to the bloodstream."
"Blocking this transporter reduces drug absorption and neutralizes their potential benefits," the study said.
"By contrast, drugs whose levels are boosted in the presence of grapefruit juice appear to block an important drug metabolizing enzyme, called CYP3A4, that normally breaks down drugs."
Among the drugs affected by consumption of grapefruit, orange and apple juices are: etoposide, an anticancer agent; beta blockers (atenolol, celiprolol, talinolol) used to treat high blood pressure and prevent heart attacks; and certain antibiotics (ciprofloxacin, levofloxacin, itraconazole).
The drug-lowering interaction also affected cyclosporine, a drug taken to prevent rejection of transplanted organs, and more drugs were expected to be added to the list as the research continued.
Bailey said patients should consult with a doctor about taking medications with juice, and stick to plain water when taking most medications.
"This is just the tip of the iceberg," Bailey said. "I'm sure we'll find more and more drugs that are affected this way."

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